Carcinogenicity testing
Also on transgenic animals
We have an extended experience in the conduct of carcinogenicity studies since we have in-house from 4 to 8 running each year.
Studies
Duration and strains
- 104 or 78 weeks for standard strains: SD, Wistar Han, Wistar, Fischer, CD-1, B6C3F1, C57Bl6
- 6 months for: P53, rasH2 and XPA knock-out
Historical data:
- Available for the different strains.
Routes of administration:
- Oral: gavage, dietary admixtures
- Parenteral: subcutaneous, intramuscular, intraperitoneal
- Dermal
Specialty services
- Genomics: a very extended number of tissues can be collected and analyzed, including tumors (PCR, Affymetrix micro-chips).
Support services
- Dedicated customized unit for the preparation of dosage forms
- Analytical chemistry for dosage forms analysis (results obtained prior to the administration)
- Toxicokinetics
- Statistical analysis
CIT Services
