Carcinogenicity testing

Also on transgenic animals

We have an extended experience in the conduct of carcinogenicity studies since we have in-house from 4 to 8 running each year.

Studies

Duration and strains

  • 104 or 78 weeks for standard strains: SD, Wistar Han, Wistar, Fischer, CD-1, B6C3F1, C57Bl6
  • 6 months for: P53, rasH2 and XPA knock-out

 

Historical data:

  • Available for the different strains.

 

Routes of administration:

  • Oral: gavage, dietary admixtures
  • Parenteral: subcutaneous, intramuscular, intraperitoneal
  • Dermal

 

 

Specialty services

  • Genomics: a very extended number of tissues can be collected and analyzed, including tumors (PCR, Affymetrix micro-chips).

 

 

 Support services

  • Dedicated customized unit for the preparation of dosage forms
  • Analytical chemistry for dosage forms analysis (results obtained prior to the administration)
  • Toxicokinetics
  • Statistical analysis

 

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Our Partners
New toxicity assessment using human and embryonnic stem cells New efficacy models

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